Hypertension, and resistant hypertension in particular, is a condition with multiple significant health implications.

The World Health Organisation predicts that for every 2mm hg (mercury) of elevated blood pressure, the 10 year risk of heart attack and stroke are increased by seven and ten per cent respectively.

Uncontrolled hypertension has an important role in the development of diseases of the major blood vessels that come out of the heart. Therefore, uncontrolled blood pressure has huge implications for this group of patients. This often silent condition is generally under diagnosed and is therefore by definition difficult to treat.

Renal denervation is a novel therapy that addresses hypertension very effectively.

The kidneys have long been known to be a major contributing factor in high blood pressure, causing blood vessel stiffness and salt and water retention. Renal denervation is a technique in which energy is delivered to the nerve supply of the kidneys thus selectively “quietening” the nerve impulses and removing the stimulant for high blood pressure.

A thin catheter is inserted into the blood vessels, usually via the groin, and directed to the renal arteries where radiofrequency or ultrasound energy is used to deaden the nerves. Both short term and longer term studies have shown a sustained significant reduction in blood pressure, decreasing the risk of heart attack and stroke.

Dr Tito Kabir and Dr Robert Smith launched the renal denervation programme at Harefield Hospital. Armed with extensive experience of second generation denervation systems, they offer patients a robust screening service and multi disciplinary team approach to hypertension treatment. They fully expect this novel treatment modality to continue to develop and provide excellent results in appropriate patients.  


Dr Tito Kabir

Consultant cardiologist





Dr Robert Smith

Consultant interventional cardiologist